http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115057758-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e63cf568229396478feabbdc84beb59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C22-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C22-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-26 |
| filingDate | 2022-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6181edc510e8077a5444f1b594ff19fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_622d3206dc0c5fa7448c435838e387e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab3c977998250a09c1e1862ba2497099 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05a64af98ab8fc411ac0ed95be64c729 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b39b113b75631a8d95804554deb02f35 |
| publicationDate | 2022-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115057758-A |
| titleOfInvention | A kind of fluorine-containing 1,4-diene compound and derivative, site-selective synthesis method and application |
| abstract | The invention discloses a fluorine-containing 1,4-diene compound and derivatives, a site-selective synthesis method and application, including branched-chain compound I, straight-chain compounds II and III; the preparation method comprises the following steps: 1: The olefin, difluorocyclopropane, metal rhodium catalyst, phosphine ligand, additives and solvent are fully mixed and dissolved under nitrogen atmosphere; Step 2: The mixture obtained in Step 1 is fully reacted at 100°C; Step 3: The After the reaction product obtained in step 2 is cooled, separated and purified, the fluorine-containing 1,4-diene compound and its derivatives can be obtained; the raw materials of the invention are simple and easy to obtain, the synthesis route is simple, the yield of the target compound is high, and the selectivity is good. , in the experiment, it has high yield and excellent selectivity to synthesize branched and straight-chain fluorine-containing 1,4-diene compounds; it can be applied to the modification of biologically active molecules, site-selective synthesis of complex fluorine-containing 1,4-diene compounds ,4-diene compound, showing the potential value of its synthetic application. |
| priorityDate | 2021-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.