http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115040488-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbbbe15755c684fa82d329589c384d69 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| filingDate | 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20a3764c07e7d60a866b7c7c745e8d1d |
| publicationDate | 2022-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115040488-A |
| titleOfInvention | A kind of desloratadine tablet and preparation process thereof |
| abstract | The invention discloses a desloratadine tablet and a preparation process thereof, relates to the technical field of desloratadine, and comprises loratadine and an auxiliary reactant, wherein the auxiliary reactant is mainly composed of corn starch, calcium hydrogen phosphate, Microcrystalline cellulose, hydroxypropyl cellulose, talc, magnesium stearate. The present invention further removes impurities such as organic solvents and reaction drugs that may remain on the outer surface of the desloratadine crystal by adopting the purification process of redissolving crystallization and washing with water, and the acetone-tetrahydrofuran mixed solvent can effectively remove the impurities carried in the crystal. The desloratadine crystals can be further purified by the process of gradual precipitation and crystallization of desloratadine, which will leave the impurity components in the solution, and then separated by filtration to further purify the desloratadine crystals. Impurity components that may be carried on the outer surface, thereby ensuring the purity of desloratadine crystals. |
| priorityDate | 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.