http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115028655-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1b95a0151fe6cf57f119866e3a10c11 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-083 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 |
filingDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0617a17d93644b02baaf69afbcf1cf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_decb992e700d3328b55beab4d993a387 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_802a31e30ebdaddf1ee17401a590c026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afbc14c60b1b7c3bfca51bc5c7b33acd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_361cca7255c3d68e928c4e91da826b44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5ff6d866882f7c9138865fe71265a10 |
publicationDate | 2022-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115028655-A |
titleOfInvention | A kind of 2-trifluoromethyl-3-iodo-indole compound and preparation method thereof |
abstract | The invention discloses a 2-trifluoromethyl-3-iodine-indole compound and a synthesis method thereof. The structural formula of the compound is: Wherein, R 1 = hydrogen, methyl, methoxy, fluorine, bromine, chlorine, iodine; R 2 = hydrogen, 2-(trimethylsilyl)ethoxymethyl, methyl, benzyl, n-butyl . In the present invention, indole is used as raw material, potassium iodide is used as iodine source, 1-(trifluoromethyl)-1,2-pheniodonyl-3(1H)-ketone is trifluoromethyl source, and under the action of copper nitrate, high-efficiency A series of 2-trifluoromethyl-3-iodoindoles were constructed. It has the advantages of simple and easy-to-obtain raw materials, simple reaction operation, mild conditions, and environmental friendliness. The 2-trifluoromethyl-3-iodoindole compounds synthesized by the method of the invention have broad application prospects in related fields such as organic synthesis, medicinal chemistry and the like. |
priorityDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.