http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115024274-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b70b705e183d3d94133c1373c3411f1e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0356 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61D1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61D1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 |
filingDate | 2022-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20eb8a573b3c065c5244301bb6669478 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cae42ca713020fe28c6e2146a17f042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be35eabdd62c591830b6529f6f198e23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21fa856b71625db8209213fbf812de46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88a6a7560be5c60dceb35dcc44041827 |
publicationDate | 2022-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-115024274-A |
titleOfInvention | An animal model of cortical pacing inhibition and its experimental construction method |
abstract | The invention provides an animal model of cortical pacing inhibition and a method for constructing a model experiment, wherein the occipital lobe of the experimental group is injected with photosensitive protein virus to transfect glutamatergic neurons, and the occipital lobe of mice in the control group is injected with empty load The glutamatergic neurons were transfected by the virus; and the optical fiber was implanted at the virus injection site and the induced CSD model was constructed; the experimental group and the control group were subjected to 467nm blue light through the implanted optical fiber, starting from 1mW light intensity and 10mW The light intensity was continuously increased as the end point for irradiation to activate the cation channels on the glutamatergic neurons in the occipital lobe of the mice in the experimental group, and to monitor the cortical electrophysiology and cerebral blood flow of the mice. Occurrence of CSD. The above animal models can simulate the symptoms of clinical migraine attacks. |
priorityDate | 2022-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.