http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115010761-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e164bcc4bd54075650f89b687ea057ff |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-33 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42bb9badf8ec8e11e1d1f3032279e2c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddfe4efaf599344e7fc7ec18804467d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c06b04b2881a03833c1819cb2f05e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf59b5605dfa8a55dba4affef1e951b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a4b9b0c944bb2106f3db48d57298783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d1766dd1d37b3e56397ae7ad17449e0 |
| publicationDate | 2022-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-115010761-A |
| titleOfInvention | A Class of Phosphorescent Cyclometallic Platinum Complexes and Their Applications |
| abstract | The invention discloses a kind of phosphorescent cyclometallic platinum complexes whose structural formula is represented by formula I or formula II; formula I Formula II Among the cyclic metal platinum complexes containing different conjugated systems of the present invention, the platinum complexes coordinated with the monodentate ligand imidazole and its derivatives have the characteristics that their own phosphorescence intensity and life are enhanced with the increase of the viscosity in the environment, and can be The change of the viscosity value in the in vitro and in vivo environment was calculated by the change of the self-phosphorescence lifetime value of the complex; in addition, this type of complex has anti-tumor activity, and also has the targeting function of specific subcellular organelles such as mitochondria and nucleus, which can occur in living cells. Two-photon phosphorescence lifetime imaging is used to specifically monitor the viscosity changes of subcellular organelles during apoptosis; this type of cyclic metal platinum complexes can be used in fluorescent probes for in vitro solution viscosity detection, as well as in cell imaging and fluorescent coloring materials. High sensitivity, lower detection cost, convenient operation, rapid determination and real-time detection. |
| priorityDate | 2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.