| abstract |
This article discloses an application of modified hyaluronic acid in medical cosmetic injection filling reagents, specifically, polyvinyl alcohol is cross-linked with silk fibroin and hyaluronic acid. Different from general hyaluronic acid medical aesthetic injection filling reagents, the present invention uses hyaluronic acid and silk fibroin with excellent biocompatibility as raw materials, and then mixes polyvinyl alcohol with them to prepare silk fibroin-polyvinyl alcohol- Hyaluronic acid hydrogel. The modified hyaluronic acid prepared by the method has very good improvements in hydrogel mechanical properties, degradation properties, swelling properties, etc., and has injectability, and has a good application prospect in the field of medical and aesthetic injections. |