http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114989067-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52
filingDate 2022-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114989067-B
titleOfInvention A kind of synthetic method of paroved intermediate
abstract The application provides a method for synthesizing an intermediate of parovede, comprising the following steps: S1. Mixing the starting compound 6,6-dimethyl-3-oxabicyclo[3.1.0]hexane shown in formula I Alk-2-ketone and a compound containing an amino group are reacted to obtain a compound shown in formula II; S2. Mix the compound shown in formula II and a compound containing a sulfonyl group under basic conditions, and react to obtain a compound shown in formula III Compound; S3. The compound represented by formula III The target compound represented by VI is obtained by two different methods. The synthetic method of the present application can effectively synthesize 6,6-dimethyl-3-azabicyclo[3.1.0]hexane. The synthetic method is simple in operation, low in cost and high in yield, and is suitable for industrial production.
priorityDate 2022-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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