Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a38a062781e4e44718aa12bb10a153b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6df84670d27f33e9fce81e1fb1a9a70c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 |
filingDate |
2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_942870555ea41b5f1fea04039d1cb7d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae9afd8dbea5df816722cdedb5453cba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9062d6587d6409245eafb7138c9e12cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_630b050c59625fd1634655a41b97ec86 |
publicationDate |
2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114989060-A |
titleOfInvention |
A kind of preparation method of briracetam |
abstract |
The present invention provides a preparation method of briracetam, which comprises the following steps: 1) compound R-4-propyldihydrofuran-2-ketone of formula I reacts with compound L-2-aminobutanamide of formula II to obtain Intermediate III; 2) Intermediate III is reacted with a brominating reagent to obtain intermediate IV; 3) Intermediate IV is closed under the action of a base to obtain briracetam. The method has simple synthesis steps and high yield, provides a new route for the synthesis of briracetam, and has strong industrial application prospects. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116573992-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116573992-A |
priorityDate |
2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |