| abstract |
The invention provides a method for synthesizing cyclopropylamine, which solves the technical problems of long reaction time, difficulty in obtaining reaction raw materials and harsh reaction conditions in the existing synthesis method. The method for synthesizing cyclopropylamine is as follows: after 1,3-dichloropropane and sodium cyanide solution are reacted in reflux at 60-100 DEG C, cooled and allowed to stand for stratification, the upper layer is taken for rectification, and the unreacted 1,3-dichlorohydrin is recovered. Chloropropane to obtain 4-chlorobutyronitrile mother liquor; react the 4-chlorobutyronitrile mother liquor obtained in step S1 with sodium hydroxide solution, and the temperature is controlled at 60～100 ° C to obtain an aqueous solution of cyclopropanecarboxamide; The propylformamide aqueous solution reacts with sodium hypochlorite solution and NaOH solution at 100°C, collects fractions with a boiling point of 49-51°C, and obtains the product cyclopropylamine after drying; it can be widely used in the field of chemical technology. |