http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114972837-A

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filingDate 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efe6908f951ae0433a4ce5342a4e8139
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_384e8acfb2bf67513f6e11ddb944c357
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publicationDate 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114972837-A
titleOfInvention A method for identifying microsatellite instability states from pathological pictures based on RNN
abstract The invention provides a method for recognizing the unstable state of microsatellites from pathological pictures based on RNN. First, a target pathological section map obtained by staining a patient's tissue sample with cells is obtained; Small pictures of the tissue area; classify all the small pictures as tumor area/normal area; randomly select N pre-set small pictures classified as tumor areas and use the staintools library to normalize the staining; normalize the normalized small pictures The image is input into the preset feature extraction model, encoded as an M-dimensional feature vector, and an N×M feature matrix is obtained; the N×M feature matrix is input into the pre-trained recurrent neural network prediction model, and the MSI score of the target pathological slice image is obtained. The present invention randomly selects N small pictures of the tumor area for feature encoding, adopts a cyclic neural network model for classification prediction, saves computing resources and improves the accuracy of MSI prediction.
priorityDate 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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