Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ebc81031ac698de90344898303146c2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E60-36 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
filingDate |
2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac50e27e8614f1da71fe916c1dd8e90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca55fc06c7b5b0750c6d33f2defbf0f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dce5df67e6af9b915d8beab7ac17ac5 |
publicationDate |
2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114957340-A |
titleOfInvention |
A kind of preparation method and application of binuclear iridium complex that induces ferroptosis |
abstract |
The invention discloses a dual-nuclear iridium complex whose structural formula is shown in formula (I): Wherein, the complex represented by formula (I) is named Ir-pq-2S. The present invention studies the anticancer activity and mechanism of the binuclear iridium complex. The results show that the complex has excellent antitumor activity and photodynamic therapy activity, and can be used as a potential new therapeutic drug to induce ferroptosis and apoptosis in cancer cells. |
priorityDate |
2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |