| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-435 |
| filingDate |
2022-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91cdde6e58c6a00bec69cc191be770f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_905ae3af9b795ecead1c09e02cbc83f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e00d0da87adfc780e1763c443d0c6909
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5136e5c967a368f4010d7e042fc3195d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd1c559ec10c5ec89e307b687a42d168
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d83ed2c23b99a4bd12b6bc9034dd08b |
| publicationDate |
2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114949364-A |
| titleOfInvention |
A kind of multi-layer tissue engineering bionic periosteum scaffold and preparation method and application |
| abstract |
The invention discloses a multi-layer tissue engineering biomimetic periosteum support, a preparation method and application, and relates to the fields of polymer materials and biomedical materials. The multi-layer tissue-engineered biomimetic periosteal scaffold of the present invention comprises layers of superimposed mineralized nanofiber membrane-cell composite layers, and the mineralized nanofiber membrane-cell composite layer comprises a mineralized nanofiber membrane and is seeded on the mineralized nanofiber membrane of stem cells. The preparation method of the invention includes: electrospinning to obtain a nanofiber membrane; incubating the nanofiber membrane in a simulated body fluid to obtain a mineralized nanofiber membrane; inoculating stem cells on the mineralized nanofiber membrane to obtain a mineralized nanofiber Membrane-cell composite layer; the mineralized nanofiber membrane-cell composite layer is superimposed layer by layer to obtain a multi-layer tissue-engineered bionic periosteal scaffold. The invention also provides the application of the multi-layer tissue engineering bionic periosteum scaffold in the preparation of bone growth promoting materials. The invention simulates the complex anatomical structure in the natural periosteum and has good osteogenic properties. |
| priorityDate |
2022-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |