abstract |
Compositions and methods for treating gliomas and converting glioma cells into neurons are provided. The composition contains an effective amount of SKL2001 and may also contain one, two, three or four of SB431542, LDN193189, CHIR99021 and DAPT. Pharmaceutical compositions containing SKL2001 with one, two, three or four of SB431542, LDN193189, CHIR99021 and DAPT are provided. Also provided are articles of manufacture containing one or more sealed containers containing one, two, three or four of SKL2001 and SB431542, LDN193189, CHIR99021 and DAPT. The article of manufacture may contain printed material that provides instructions for the compound to be used in the treatment of glioma. |