| abstract |
The invention relates to an androstendrolone derivative with antitumor activity, a preparation method and application thereof, and belongs to the technical field of antitumor drugs. Such as the following formula (I) compound: These compounds can target prostate tumor cells, have good inhibitory effect on DU-145 and PC-3 cells, and are less toxic to normal cells. It can play an active role in many aspects such as inhibiting tumor cell proliferation, promoting tumor cell apoptosis, pyroptosis, and causing tumor cell DNA damage. |