| abstract |
Anti-CLEC12A polypeptides typically include an amino acid sequence with at least 90% amino acid similarity to SEQ ID NO:14. In certain embodiments, anti-CLEC12A polypeptides can be incorporated into anti-CLEC12A biologicals. In some of these embodiments, the anti-CLEC12A biologic can be a bispecific killer cell adapter (BiKE), a trispecific killer adapter (TriKE), a tetraspecific killer adapter (TetraKE) ), pentaspecific killer cell adaptor (PentaKE), bispecific T cell adaptor (BiTE), trispecific T cell adaptor (TriTE), tetraspecific T cell adaptor (TetraTE), Pentaspecific T cell engager molecules (PentaTE), chimeric antigen receptors, intact antibodies, antibody-drug conjugate (ADC) molecules, targeted delivery constructs or labelling constructs. |