Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
filingDate |
2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_151315817545d6123e456bf8d2a6553b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03691c78c0133438617c21ecd2b82b73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54e26599697c339c3a7a9169043255d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d5dd9e93e7d51a235fe63e844e6d6fe |
publicationDate |
2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114929343-A |
titleOfInvention |
Methods of treating multiple myeloma with bispecific anti-BCMA x anti-CD3 antibodies |
abstract |
B cell maturation antigen (BCMA) is expressed on malignant plasma cells. The present invention provides methods of treating multiple myeloma using bispecific antibodies (bsAbs) that bind to both BCMA and CD3 and activate T through the CD3 complex in the presence of BCMA-expressing tumor cells cell. In certain embodiments, the bispecific antigen binding molecules of the invention are capable of inhibiting the growth of BCMA-expressing tumors. |
priorityDate |
2019-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |