http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114920269-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2006-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2006-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01D7-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01D7-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01D7-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01D7-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01D7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01D7-26 |
filingDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114920269-B |
titleOfInvention | A kind of preparation method of sodium bicarbonate for injection |
abstract | The invention relates to the technical field of pharmaceutical preparation, and discloses a preparation method of sodium bicarbonate for injection, comprising the following steps: (1) adding purified water into a reaction vessel, starting stirring, heating up and introducing carbon dioxide gas, and adding sodium carbonate , Sodium sulfide nonahydrate, stir until dissolved, and after testing the pH value is qualified, cool the solution, add ethanol solution, crystallize, and centrifuge to obtain wet crude product; (2) Refining process: add purified water to the reaction vessel, pass Carbon dioxide gas, add the wet crude product after heating up, stir until dissolved, continue to add activated carbon to carry out stirring adsorption and filtration, transport the filtrate to the reaction vessel in the clean area, cool down, turn on stirring, add ethanol solution, continue to cool down, crystallize, and centrifuge After drying, it is obtained. The invention greatly reduces the production cost, and has the advantages of simple preparation process, easy control of reaction parameters, and high yield and purity of the prepared sodium bicarbonate, which is suitable for industrialized large-scale production. |
priorityDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.