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publicationDate 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114917971-A
titleOfInvention Microfluidic chip and detection method based on microdroplet hydrogen sulfide trace detection
abstract The invention discloses a microfluidic chip for detecting trace amounts of hydrogen sulfide based on microdroplets. The microfluidic chip cures a channel pattern on a film plate on a silicon substrate coated with photoresist by an ultraviolet lithography machine, and then A microfluidic chip is formed by pouring polydimethylsiloxane (PDMS) on a silicon substrate; the channel pattern includes a polygonal channel, and the polygonal channel includes an oil-phase solution inlet, and the oil-phase solution inlet channel extends forward and After the bifurcation channel is formed on both sides, it is finally closed and formed into a polygon. One side of the closed point is connected with the inlet channel of the hydrogen sulfide sample solution to be tested and the mixing channel of the Raman reagent solution channel, and the other side of the closed point is connected with a mixing channel to improve the mixing efficiency. S-shaped channel, the rear section of the S-shaped channel is connected with a detection channel, and the end of the detection channel is provided with a waste liquid outlet. The invention utilizes the principle that hydrogen sulfide can etch silver nanoparticles, and realizes the detection of hydrogen sulfide content in human serum.
priorityDate 2022-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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