http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114907438-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_403d5c0957964cdc7754ec54497e126a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 |
| filingDate | 2022-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0fbaabd6e5741a2b1ca86df3ac07833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b94de49dfd200c3c3166878f1da926a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01c402d83a5344cb32c66e3bbe24cecc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47173f5b52d0d7ef2ec19dce92e289af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6185dec6da80509c31e98b0e6173db6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3ba42857aa639102c003cfb47dbf7d9 |
| publicationDate | 2022-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114907438-A |
| titleOfInvention | A kind of lupin alcohol coupling triphenylphosphine derivative and its preparation and application |
| abstract | The invention discloses a lupin alcohol-coupling triphenylphosphine derivative and its preparation and application, belonging to the technical field of medicine. The structure of the lupin alcohol-coupled triphenylphosphine derivative is: where n=1, 2, 3, 4. In the present invention, lupin alcohol is used as a raw material, and an aliphatic straight chain containing bromine atoms is first introduced through an esterification reaction with its C-3 hydroxyl group as a connecting point to synthesize an intermediate compound; and then the intermediate compound is salified with triphenylphosphine. reaction to obtain the target product. The lupin alcohol-coupled triphenylphosphine derivative of the invention has good biological activity on the growth of human liver cancer HepG-2, human lung cancer A549 and human breast cancer MCF-7 and MDA-MB-231 cells, and has the advantages of being developed as an anti-cancer drug. Potential for new oncology drugs. |
| priorityDate | 2022-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.