http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114874123-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f74075071681158594c6d21bc4fb2db |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-00 |
| filingDate | 2022-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a98a247cf3d3ce59c94d885c5ee20b55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54f764fe1cf4ce31d564c70507a85910 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61448fcdc8bb1e8539c9097ed6a865d9 |
| publicationDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114874123-A |
| titleOfInvention | A near-infrared & two-photon dynamic dual-mode highly stable fluorescent dye, NTR & HClO probe, synthesis method and application |
| abstract | The invention relates to the technical field of ROS&AOS detection, and specifically discloses a single-molecule dual-mode excitation probe and its synthesis process and application. The structural formula of the single-molecule dual-mode excitation probe is as follows: . In the present invention, the structure of traditional cyanine is optimized first, and a nitrophenylbenzyl structure compound CY-8 with a large absorption coefficient is synthesized, thereby enhancing the stability of the near-infrared framework (CY-8). Secondly, in the present invention, a two-photon response part (compound 2) is formed by combining naphthol-biphenylene dinitriles; then CY-8 and compound 2 are connected to obtain CYNA-CN. The compound has dual-mode (near-infrared, two-photon) excitation fluorescence function, so it can independently detect nitroreductase (NTR) and hypochlorous acid (HClO) in cancer cells in a non-interfering excitation manner. |
| priorityDate | 2022-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.