| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08dde60e3e0ca1e6ffaa5143e5c8477a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4741 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4741
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
2022-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b09bffcb535ee2a79db335c3721f74d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f5f30c106dc11bb5e7fa332174efe7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71bdb35d169a750e6e57168b917b140e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54aa42906acf2b07ca95d5c390abb9ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2c3311d57bcb5bbc324b61ffb7f46b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d60173bfe32d590ae0c832dda2f2f6f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80e4cdf46ff1c83b25d621b437ad5917
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b9d8d24c745555391899a1f6241b1b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d5d6cf2d8f6752af91e8d56dd1c56f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0688c3429d5fd887033624cf5d05717c |
| publicationDate |
2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114869999-A |
| titleOfInvention |
Application of chelerythrine combined with polymyxin E in the inhibition of polymyxin E-resistant bacteria |
| abstract |
The invention discloses the application of chelerythrine combined with polymyxin E in inhibiting polymyxin E-resistant bacteria, and the polymyxin E-resistant bacteria are mcr-positive bacteria. Experiments have shown that chelerythrine can synergistically inhibit polymyxin E (such as mcr-1-positive Escherichia coli ZJ807, mcr-8-positive Klebsiella pneumoniae KP91, mcr-9-positive Salmonella SLM183), and reduce the reduction of polymyxa. The resistance to polymyxin E was reversed at the same time. The chelerythrine can restore the inhibitory effect of polymyxin E on polymyxin E-resistant bacteria. The invention has important application value. |
| priorityDate |
2022-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |