http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114858917-A

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filingDate 2021-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb3100357f1bb5a674267dca208c5d6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_297fecc7dd5cecbcdf752b292b2a0c33
publicationDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114858917-A
titleOfInvention An analytical method for real-time dynamic monitoring of cell transmembrane transport of small organic molecules
abstract The invention discloses an analysis method for using QCM-D to dynamically monitor cell transmembrane transport of small organic molecules in real time, and belongs to the technical field of cell transmembrane transport small molecule process monitoring and biosensors. The invention creatively combines the QCM-D with nanogram-level sensitivity with the small molecule transmembrane transport mechanism, and provides a real-time dynamic monitoring of the transmembrane transport of organic small molecules in cells under the stimulation of different media by using the QCM-D technology. The new method for online analysis, including the construction of sensing interface, the adhesion of cells in the flow cell, the monitoring of the transmembrane transport of organic small molecules by the adherent cells under the stimulation of different media, and the control of the flow system conditions, has high sensitivity, simple operation, in situ non-destructive, The advantages of real-time dynamic monitoring and other advantages are expected to be popularized and applied in research fields such as physiology, pharmacology, basic medicine and clinical diagnosis.
priorityDate 2021-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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