| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fb8da72a2135e6aa786104d17dc6e9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55a470495161fc36cab353965d47e9b2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate |
2021-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3da0dbaf11356c6dc68e7038aeecacd4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45da236871e9d82d2031f579e58e5e8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5016f26d3b9db75e242bb406f3ef041d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a25957051d22b604b5d56dc9fd8bd53d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a7163f40b2a5d7e214e78a87a72d37f |
| publicationDate |
2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114858763-A |
| titleOfInvention |
A Kind of Specific Fluorescent Probe for Detecting Human Serum Albumin and Its Application |
| abstract |
The object of the present invention is to provide a specific fluorescent probe for detecting human serum albumin, which can be specifically hydrolyzed by human serum albumin in human serum, plasma or urine to generate a fluorescence emission spectrum with Products with significantly different substrates. The content of albumin was quantitatively detected by measuring the amount of hydrolysate produced in unit time. The specific probe is N-n-butyl-4-hydroxy-1,8-naphthalimide parent C-4-hydroxy-substituted bibenzoyl ester derivatives. Its general structural formula is shown in formula (1), wherein R is any one of -F, -CF 3 , and -NO 2 . The specific probe of the present invention has the following outstanding advantages: (1) high specificity; (2) cheap and easy to obtain; (3) high sensitivity; (4) good detection reproducibility. |
| priorityDate |
2021-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |