| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f19a031ab4489e8e59f829d009f4afd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate |
2022-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f59f7d105dad23acf27e76136c004dfb |
| publicationDate |
2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114854816-A |
| titleOfInvention |
A keratinocyte exosome-mediated approach to promote hair growth |
| abstract |
The invention discloses a method for promoting hair growth mediated by exosomes of keratinocytes, and relates to the technical field of hair growth. Cultured in medium at 37°C and 5% CO2; HFSCs were cultured at 37°C and 5% CO2 in fully grown human hair follicle stem cell culture medium and serum with fisetin (>96.0% purity), RNA was extracted from cell and skin samples using HighPureRNAIsolationKit and RNeasyFibrousTissueMiniKit, respectively, cDNA synthesis and quantitative reverse transcription polymerase chain reaction (qRT-PCR) were performed, samples were analyzed, and gene expression levels were normalized to the corresponding β-actin gene levels . The keratinocyte-derived exosomes of the present invention can activate hair follicle stem cells and thereby induce hair growth with few side effects and satisfactory effects. |
| priorityDate |
2022-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |