| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00d27136cec99c04ab41cdb69cbacc7c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A40-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0318 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2022-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5f88bb325eb79d20aaaf075822166c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4520fc0624770d353165a74ec5c241cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2f1e0335afc925b97bc62074e7ea654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b35e7f2eb17cd8136cb30af41b7bf094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b03582cac8796f6808d73c26b42456a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf8c0305081f943c0a26dc0a260073f5 |
| publicationDate |
2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114854748-A |
| titleOfInvention |
apoc1 gene promoter and its application and animal model and method constructed therefrom |
| abstract |
The present invention relates to the technical field of nerve cell labeling method and related animal models, in particular to the apoc1 gene promoter and its application and the animal model and method constructed by the same. The nucleotide sequence of the apoc1 gene promoter is shown in SEQ ID NO. 1, which can be used to label or manipulate microglial cells, and a zebrafish transgenic line can be constructed by using this promoter. This solution can solve the technical problem of the lack of an operable promoter sequence for labeling microglial cells in the prior art. The zebrafish transgenic line constructed using the apoc1 gene promoter is a very good zebrafish animal model for studying microglial cells, which can be used for the mechanism study of the role of microglial cells in neurodegenerative-related diseases. For drug screening and drug efficacy testing, it has good application prospects. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114717262-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114717262-A |
| priorityDate |
2022-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |