| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db304b0b56a0b1201d8754af806cd838 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4723
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 |
| filingDate |
2022-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c85f13937ac794083d9409cb3ca807c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3f5b796523e04347f87bc4a28dc6450
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aee7aa641454c69781805136bb8e2786
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c3888cca16bfe157679c4cb93a8963
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eb40d0b8e1eab5d3ea1800f82ea0beb |
| publicationDate |
2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114854652-A |
| titleOfInvention |
Application of BCG gene BCG_1820 in the preparation of recombinant BCG for tuberculosis vaccine |
| abstract |
The invention provides the application of BCG gene BCG_1820 in the preparation of tuberculosis vaccine recombinant BCG, and specifically provides a BCG recombinant bacterium ΔBCG_1820 in which the gene BCG_1820 is knocked out. The invention also provides a preparation method of the BCG recombinant bacteria and its application in preparing a tuberculosis vaccine. The BCG recombinant bacterium ΔBCG_1820 provided by the present invention can obviously induce macrophages to produce more antibacterial peptides, give the host a stronger ability to resist tuberculosis infection, and has the potential to be used as a candidate vaccine for tuberculosis. |
| priorityDate |
2022-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |