http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114854556-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b741ec085646f4ce9c814a01617717e8
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filingDate 2022-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c8d506553d8e1e720454774489eab8f
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publicationDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114854556-A
titleOfInvention Device and method for cell-bead capture pairing for single-cell omics analysis
abstract The present invention provides a cell-microbead capture pairing device and method for single-cell omics analysis, the device comprises: a microwell capture layer, which comprises: a microwell array composed of several microwells, each microwell Including cell trapping wells and microbead trapping wells connected by connecting channels; and auxiliary trapping structures by including: 1) physical barriers between cells and microbeads, 2) application of hydrodynamics, 3) implementation of external physical fields The separation of cells and microbeads is formed in any way; through the combination of the two, one cell and one microbead fall into each cell trapping well and bead trapping well, respectively, completing the one-to-one capture pairing of cell-microbeads. The invention overcomes the problem of low pairing efficiency caused by random pairing in the prior art, and the provided chip has simple structure and process, low cost, short processing time, simplified operation steps, and realizes one-to-one cell-microbeads. efficient capture pairing.
priorityDate 2022-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 22.