| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33a62710796e131599043055d399597f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 |
| filingDate |
2022-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adcd857170291ca6fe0b4093688c3ce2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61ee0c2af6435bb3a466296202cfe5b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98a4006169c7acb588435d339da05047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1512f9651004eb55f15bcb9b43e71ec0 |
| publicationDate |
2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114848919-A |
| titleOfInvention |
Composite hydrogel for TBI immune regulation and tissue repair and preparation method thereof |
| abstract |
The invention discloses a composite hydrogel for TBI immune regulation and tissue repair and a preparation method thereof. The composite hydrogel is composed of a brain acellular matrix dBECM, methacrylated gelatin GelMA and a photocrosslinking initiator LAP It is obtained by photocrosslinking after mixing. dBECM provides the composite hydrogel with a suitable microenvironment for cell survival and growth and induces the differentiation of mesenchymal stem cells into neural cells, while GelMA provides the composite hydrogel with appropriate mechanical strength and photosensitivity. The composite hydrogel of the present invention has the advantages of two components, and combined with mesenchymal stem cells, it can regulate the immune response after TBI, improve the neuroinflammatory microenvironment and promote tissue repair. |
| priorityDate |
2022-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |