abstract |
An immunotherapy composition and use thereof, comprising: lipophilic muramyl dipeptide (MDP) analog-liposome-encapsulated muramyl tripeptide phosphatidylethanolamine, the immunotherapy composition containing mycobacterial cell wall components , is a natural immune stimulator, and its liposome preparation is easily taken up by macrophages in tissues (especially the lung), which is a common metastatic site of osteosarcoma. It has a variety of biological response regulating activities, which can stimulate the host defense mechanism and inhibit tumor metastasis; it can enhance the movement and migration of peripheral lymphocytes and tumor-infiltrating lymphocytes in cancer patients, and can cause damaged tumor-infiltrating lymphocytes in melanoma patients. The ability of cell movement and migration is restored. |