| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e82a5506a5b2996912d0f694a64daf2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351 |
| filingDate |
2022-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f02fc3a3b01e0dfef446222668db991
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f75c4b89ec99d751a365d4a843bc7e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95cc64ce96da5933fe764dc4451d7c08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f60a69a6640e5e2cc2b1b88aaeca4de7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0e2900ad16887a78f06853801d3c303
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54d9d4d5d88d2ef1f45c0ba33e6d4308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bbb813418925e222c3e134d584089ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ae1a0d9d4fade093ac977daab6703f |
| publicationDate |
2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114848626-A |
| titleOfInvention |
Application of a hydroxysafflor yellow A in the regulation of ischemic stroke |
| abstract |
The invention discloses the application of hydroxysafflor yellow A in the treatment of ischemic stroke model drug efficacy. The present invention adopts the above-mentioned hydroxysafflor yellow A to regulate ischemic stroke, and generate neuroprotection through autophagy. The function of regulating autophagy mainly has two aspects. One is the increased expression of microglia M2 type that promotes autophagy, reducing inflammation and oxidative stress damage under OGD/R injury, thereby reducing neuronal damage; Hydroxysafflor yellow A directly targets neuronal autophagy activation for neuroprotection. Therefore, hydroxysafflor yellow A has positive significance in the preparation of drugs for promoting autophagy in the treatment of ischemic cerebrovascular diseases. |
| priorityDate |
2022-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |