| abstract |
The present application relates to the technical field of molecular biology, and provides a fluorescent probe for detecting Mycobacterium tuberculosis. The fluorescent probe includes a metabolic group and an aggregation-induced luminescent group, and the metabolic group is connected to the aggregation-induced luminescent group through a chemical bond , metabolic groups for the synthesis of Mycobacterium tuberculosis cell wall peptidoglycan. The fluorescent probe provided in the present application synthesizes Mycobacterium tuberculosis cell wall peptidoglycan through the contained metabolic groups, and accumulates in a large amount on the Mycobacterium tuberculosis cell wall in the form of metabolic labeling, and the aggregation-induced luminescent groups generate fluorescent signals due to aggregation. , so as to realize the detection of Mycobacterium tuberculosis. In addition, the fluorescent probe can detect Mycobacterium tuberculosis quickly and conveniently, and has strong specificity and high sensitivity. |