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filingDate 2022-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5721bc731701230f31a261b713663ed8
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publicationDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114822824-A
titleOfInvention Construction of a prediction model for the efficacy of RAS and BRAF gene wild-type colorectal cancer patients with liver metastases based on radiomic features
abstract The invention belongs to the technical field of intelligent medical treatment, and in particular relates to a prediction model of curative effect of RAS and BRAF gene wild-type colorectal cancer liver metastasis patients based on imaging omics features and its application. The present invention has successfully constructed a model for predicting the curative effect of liver metastases from RAS and BRAF gene wild-type colorectal cancer patients receiving advanced first-line bevacizumab combined with chemotherapy based on the CT imaging omics features before treatment. 1000 times Lasso-Logistic analysis was used to obtain 7 image group characteristics, and the multivariate logistic regression method was used to build a radiomics prediction model. The model constructed by the present invention starts from clinical practical problems and has important clinical application and promotion value.
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