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filingDate 2022-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114807299-B
titleOfInvention A dual-luciferase method, cells and kit for detecting ADC drug activity
abstract The invention provides a dual luciferase method, cells and kit for detecting ADC drug activity. Based on the detection of dual luciferase activity, the present invention provides a new dual luciferase method for detecting ADC drug activity. In this method, antigen-negative cells and antigen-positive cells are co-cultured in the presence of ADC drugs to detect ADC The side-killing rate of drugs on antigen-negative cells and the killing rate of ADC drugs on antigen-positive cells. The detection method of the invention is consistent with the results of the existing flow detection method, and has the advantages of simple operation, high accuracy, high throughput, good repeatability, wide applicability and the like.
priorityDate 2022-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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