| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-119
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-39 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114807015-B |
| titleOfInvention |
A method for inducing the transformation of pancreatic islet alpha cells into beta cells and its application |
| abstract |
The invention discloses an induction method for promoting the transformation of pancreatic islet alpha cells into beta cells and its application. The induction method is based on the traditional induction method, and is replaced with the transformation of pancreatic islet alpha cells into beta cells on the 35th day of induced differentiation. Culture medium, while adding artemether and GABAA activator NS11394 induced to the 40th day. It has been verified that the induction method of the present invention can significantly increase the expression level of pancreatic beta cells, and is suitable for the production and clinical application of large-scale cell preparations. |
| priorityDate |
2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |