Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d496576561159f683d5fd7c887538114 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-07 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07 |
filingDate |
2021-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98df3837dab797a2f98139e1512aa7e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb948e88febbb466c44cfd1e149caa37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84c4141f4460d6710ccc347a531874b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0caeb7cb51594d5d8f6ed67a45c3a86c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_793dbcb410a0f138158aea957d6f7903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1627d31233f4b7f56f404a369612529 |
publicationDate |
2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114805457-A |
titleOfInvention |
Semi-synthetic flavonoid glycoside and its anti-inflammatory use |
abstract |
Semi-synthetic flavonoid glycosides and their anti-inflammatory uses. The invention belongs to the technical field of medicine, in particular to the synthesis of derivatives of natural products and their use in anti-inflammatory, and more particularly to a method for synthesizing flavone glycosides and their use in anti-inflammatory. In the present invention, hesperetin is used as a raw material, and benzyl-protected flavonol aglycones are synthesized through reaction steps such as oxidation and benzylation, and then a glycoside condensation reaction is carried out with fully acetylated bromo sugars to synthesize 5 flavonoid glycoside compounds. . Three compounds showed good in vitro anti-inflammatory activity and may become anti-inflammatory drugs or lead compounds. |
priorityDate |
2021-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |