http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805307-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1330a1636bc7601f63e30105f8519a7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 |
| filingDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5911d17c2749c0ac0d1aacb4f3cbf4ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b81eff8cc518badf78606a994e9dd44 |
| publicationDate | 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114805307-A |
| titleOfInvention | A kind of indole compound for preparing coronavirus therapeutic medicine |
| abstract | The invention discloses an indole compound for preparing a coronavirus therapeutic drug, and belongs to the field of chemical medicine. The indole compound represented by the general formula (I) of the present invention or a pharmaceutically acceptable salt thereof has excellent inhibitory activity against tubulin polymerization, and can destroy the cytoskeleton by inhibiting tubulin, so that the coronavirus cannot be transported , to achieve the purpose of effective treatment of viral infections. At the same time, the compounds of the present invention have better metabolic stability and longer metabolic half-life, so that the medical dose can be reduced and the administration time interval can be extended. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115504964-A |
| priorityDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.