http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805220-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bd83717fd5800ca818be4d3024678f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46ee4e64c816027b00ee4903c4999c4d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-90 |
| filingDate | 2022-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b73c87419fbb3d72249118499ce80e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70593b9666518082660640f6b0810ab0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c123a64c8fa5df97ce85ed2679149bc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab42345bcb41ff2714ce3f7003ff726f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00792beb22f2417dae834edcab5d60ad |
| publicationDate | 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114805220-A |
| titleOfInvention | A kind of preparation method of quinazolinone compound |
| abstract | The invention discloses a preparation method of quinazolinone compounds. The present invention provides a preparation method of compound 4, which comprises the following steps: in a solvent, an organic amine and compound 3 are subjected to a salt-forming reaction and then separated to obtain a salt of compound 4; the salt of compound 4 is subjected to an acidification reaction to obtain a Compound 4, the organic amine is S-garnetine and/or S-phenethylamine. The above compound 4 can be used to synthesize other quinazolinone compounds. In the preparation method for synthesizing quinazolinone compounds of the present invention, the SFC splitting technology is not used in the whole process of synthesizing the target molecule, which is lower in cost, faster in speed and larger in single batch than the target obtained in the prior art. compound, and the quinazolinone compounds were prepared with 99.5% ee value. |
| priorityDate | 2021-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.