http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805194-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2022-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114805194-B |
| titleOfInvention | A kind of continuous hydrogenation method of 2-nitropyridine derivatives and its application |
| abstract | The invention provides a continuous hydrogenation method for 2-nitropyridine derivatives, the method comprising: dissolving 2-nitropyridine derivatives (II) in a solvent, and mixing with hydrogen to form a gas-liquid mixture as a reaction raw material; The reaction raw materials are continuously fed into the fixed-bed reactor for catalytic hydrogenation, and the 2-aminopyridine derivative (I) is continuously discharged. The method of the invention can effectively control the reaction state in the reactor, can greatly increase the reaction efficiency, reduce the risk of impurity generation, and improve the yield, purity and product performance stability of the target product. After the catalytic hydrogenation reaction, the catalyst does not need to be filtered, which reduces the risk of spontaneous combustion of the catalyst, and the catalyst has no deactivation phenomenon, and the recovered catalyst can also be recovered and reused. The invention has the advantages of low cost, high yield and high purity of the 2-aminopyridine derivative (I). |
| priorityDate | 2022-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.