http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114796208-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3128c49d9d6cc01c2654df8950f4399b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 |
| filingDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21800c96621f0fcf6f0cd3fe29f16ce0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_485da8a9ab849373b93d1fc0c24cc9cd |
| publicationDate | 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114796208-A |
| titleOfInvention | Application of rapamycin in the preparation of drugs for preventing or treating hematopoietic necrosis of crucian carp |
| abstract | The invention provides an application of rapamycin in preparing a medicine for preventing or treating hematopoietic necrosis disease of crucian carp. CyHV-2 virus infection and replication in GiCF cells, rapamycin significantly inhibited the phosphorylation of mTOR and the expression of ORF121 protein at the protein level, or mediated the expression of some genes in the PI3K/AKT/mTOR signaling pathway by inhibiting the phosphorylation of mTOR The expression amount is to inhibit the replication of CyHV-2; the rapamycin of the present invention inhibits the phosphorylation of mTOR, inhibits the expression amount of some genes in the PI3K/AKT/mTOR signaling pathway, and inhibits the copy of the CyHV-2 virus. and the expression level of some viral genes, thereby inhibiting the replication of CyHV-2. |
| priorityDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.