abstract |
The invention relates to the field of medicinal chemistry, and discloses a disulfide bond compound, a preparation method and an antibacterial application thereof. The compound is effective against Sclerotinia sclerotiorum, Rhizoctonia solani, Botrytis cinerea tomato, Fusarium oxysporum, rice blast, Phytophthora capsici, Aspergillus flavus, Penicillium extensa, stone fruit brown rot, Rhizopus stolonifera, Bacterial blight, Citrus canker, Potato blackleg, Escherichia coli, Staphylococcus aureus, Candida albicans, Bacillus cereus, Listeria monocytogenes, Salmonella enteritidis showed potential inhibitory activity, and some Compounds have high inhibitory activity. The disulfide bond compound of the invention is simple to prepare, and the raw materials are cheap and easy to obtain, and can be developed into a new type of bacteriostatic agent that is green, pollution-free and sustainable. |