http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114773179-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-307 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C53-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate | 2022-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114773179-B |
| titleOfInvention | A kind of preparation method of compound I liquid composition and its use in myocardial metabolism PET imaging |
| abstract | The application provides a method for preparing a myocardial metabolism PET imaging agent trans-2-(2-(5-fluoro[ 18 F]tridecyl)cyclopropyl)acetic acid (referred to as compound I) liquid composition and the same Use, wherein, the crude product containing compound I is purified by high performance liquid chromatography; wherein, the mobile phase used in the purification step of high performance liquid chromatography includes ethanol and water. In the present application, by optimizing the experimental process scheme, by changing the amount of compound I tert-butyl ester precursor, the reaction time to reach the same labeling rate is shortened, the radioactivity of the initial 18 F ion is increased, and the labeling rate is increased, thereby improving the yield. |
| priorityDate | 2022-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.