abstract |
The invention provides a freeze-dried preparation of recombinant BCG vaccine, which contains the following components in parts by weight: 0.05 part of recombinant BCG, 1-3 parts of dextran-40, 2.5-3.5 parts of sucrose, sodium glutamate 0.2-0.5 part, potassium chloride 0.2-0.7 part, trehalose 3-4 part, Tween-80 0.005-0.015 part. The freeze-dried preparation of the recombinant BCG vaccine provided by the invention has high quantity of viable bacteria, stable properties and easy storage, and has good application value as a vaccine for preventing tuberculosis. |