| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9f8eff85227fd96744c754de382d6b2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d6c246d0171a034951d8ea4aa02f9fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a485204258a7dfd427fe33d26bb2f7 |
| publicationDate |
2022-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114761436-A |
| titleOfInvention |
Means and methods for treating subjects with HER2 and HER3 positive cancers |
| abstract |
The present invention relates to a treatment for a subject suffering from cancer using a bispecific antibody comprising a first antigen binding site and a second antigen binding site, the first antigen binding site binding ErbB- The extracellular portion of 2, the second antigen-binding site binds the extracellular portion of ErbB-3, the cancer has progressed following prior therapy. Prior treatments include: chemotherapy; monospecific bivalent antibodies that include an antigen-binding site that binds the extracellular portion of ErbB-2 or the extracellular portion of ErbB-3; or treatment with a tyrosine kinase inhibitor of ErbB-2 (TKI ) or prior treatment in combination with it. |
| priorityDate |
2019-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |