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filingDate 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114748696-B
titleOfInvention A kind of co-crosslinked double bond crosslinked biological valve material and its preparation method and application
abstract The present application discloses a co-cross-linked double-bond cross-linked biological valve material and its preparation method and application, (1) soaking the biological material in a solution containing the first functional monomer for physical infiltration; the first functional monomer The body has at least one carbon-carbon double bond and at least one group reactive with the aldehyde group; (2) adding an aldehyde-based crosslinking agent to the system of step (1) to carry out co-crosslinking; (3) will pass through the step (2) ) The treated biological material is immersed in a solution containing a second functional monomer for physical infiltration; the second functional monomer has at least one carbon-carbon double bond; (4) adding an initiator to the system of step (3) , triggering double bond polymerization. In the present application, adding a second functional monomer in the double bond polymerization step to form more large polymer cross-linking networks can increase the cross-linking degree of biological materials and improve the anti-calcification performance.
priorityDate 2021-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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