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filingDate 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114748203-A
titleOfInvention Construction method and application of a urography animal model based on cystostomy
abstract The invention belongs to the technical field of medical animal models. The invention utilizes that under sterile conditions, a surgical blade is used to puncture the bladder to form a cystostomy opening to drain urine in the bladder, and a cystostomy tube is inserted into the cystostomy opening. Absorbable surgical sutures were sutured to the cystostomy opening. A skin puncture hole was opened at the back of the neck of the rat. A subcutaneous tunnel was formed from the upper end of the bladder to the subcutaneous tissue at the skin puncture hole. The end of the cystostomy tube passed through the rectus abdominis to the After subcutaneous, the animal model is constructed by the method of piercing the skin puncture hole along the subcutaneous tunnel. During anterograde cystourethrography, a syringe containing a contrast agent was used to connect the end of the cystostomy tube, and the contrast agent was injected to display the whole process of the rat bladder and urethra. This rat animal model greatly promotes the study of the rat urinary system. It can be applied to other animals and used for reference, which is of great significance to the study of clinically relevant diseases of the human urinary system.
priorityDate 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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