| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75df1d17c60d932d89d802d7031b7bfa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
| filingDate |
2021-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b77b7cdf89ceea7985dcc98a4e6036cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8213b81e30da2f7f66661db8b2b3a395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_979b7e53e5e7cf5174897f9f6b4363c4 |
| publicationDate |
2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114736266-A |
| titleOfInvention |
Polysubstituted alkyl acid compounds and their applications |
| abstract |
The present invention discloses a polysubstituted alkyl acid compound and its application. The structure of the polysubstituted alkyl acid compound is shown in formula (I). These compounds can exert anti-tumor effects by strongly inhibiting the APC/Asef interaction. The compound of the present invention has no toxic effect on the proliferation of normal cells, has inhibitory and killing effects on various cancer cells, can inhibit the metastasis and invasion of various cancer cells, and has broad-spectrum anti-tumor activity; the compound has good water solubility. In terms of anti-tumor activity and druggability, these compounds have good development and application value. |
| priorityDate |
2021-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |