| abstract |
The invention discloses an endoscopic device for thyroid surgery based on fluorescence lifetime and Raman spectrum imaging, comprising: a light source assembly, an endoscope probe, a fluorescence lifetime image signal acquisition module, a Raman spectrum signal acquisition module, and a color image acquisition module; a host, including a control unit, an image processing unit; and a display for displaying the Raman spectral signal, the image in which the fluorescence lifetime image signal of the cancerous tissue is fused with the color image, and the image in which the Raman spectral signal and the color image are fused. The present invention utilizes Raman spectroscopy to image the autofluorescence of parathyroid glands, which can realize precise positioning of parathyroid glands; Raman spectroscopy can also achieve the location of neck tissues such as lymph nodes and adipose tissue in the central region of the thyroid gland, and combined with the fluorescence lifetime Imaging can provide the conformational state of fluorophores in neck tissue, mark cancerous tissue, and provide real-time optical-assisted localization for thyroid endoscopic surgery to distinguish each anatomical tissue. |