| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217f2be73fd6be0be36dd55803d3bec5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0682
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y106-02004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-14001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_526845287ee440b67cf71bcb3ba37213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99096c0db15beac8e31f0ad2e18676bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba317b454420535447b6482c9f693593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0afb64d936bfb975042f8701dd2edc0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f710d62ae2c1f1afc79548b6390e2279 |
| publicationDate |
2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114717195-A |
| titleOfInvention |
Cell model for screening of CYP3A7-mediated metabolic toxicity of exogenous compounds and its construction method and application |
| abstract |
The invention discloses a cell model for screening toxic exogenous compounds mediated by CYP3A7 and its construction method and application. Described a kind of cell model screened by CYP3A7-mediated metabolic toxicity exogenous compound, it is characterized in that: adopt Flp-In TM -CHO as target cell, will contain the coding DNA sequence of CYP3A7 and POR to be transfected into target cell respectively, The cell model for screening fetal metabolically toxic exogenous compounds is obtained. The model established by the invention is novel, reliable and simple, and can greatly improve the sensitivity of the cell model for screening the metabolic toxicity of exogenous compounds mediated by CYP3A7. |
| priorityDate |
2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |