| abstract |
The invention provides a 7-substituted phosphoryl quinazoline derivative and a preparation method and application thereof. The present invention provides a 7-substituted phosphorylquinazoline derivative shown in formula I, its tautomer, stereoisomer, hydrate, solvate, pharmaceutically acceptable salt or prodrug. The 7-substituted phosphoryl quinazoline derivatives have better SOS1 inhibitory effect. |