| abstract |
The invention discloses a preparation method of indoleimine diastereomer, and belongs to the technical field of organic synthesis. In the present invention, by using a silver compound as a catalyst, without adding any alkali or chiral auxiliary, the cyclohexenone amine compound and the pyridine ketene imine salt compound are reacted in an organic solvent to obtain the diastereomers of each other in one step. Constructed indoleimine. The advantages of the method for preparing indoleimine of the present invention are that it is simple and efficient, the three-dimensional structure of the product is diverse, the reaction yield is high, the scope of application of the substrate is wide, the product is easy to separate and purify, the purity is good, and it has good academic guiding significance and Industrial application value. |